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Invitrogen™ RAMP2 Polyclonal Antibody
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Sheep Polyclonal Antibody

Brand:  Invitrogen™ PA547846

Product Code. 15508342

  • € 520.00 / 100µg

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Description

Description

In direct ELISAs, approximately 25% cross-reactivity with recombinant human (rh) RAMP2 is observed, and less than 1% cross-reactivity with rhRAMP1 is observed. Reconstitute in sterile PBS to a final concentration of 0.2 mg/mL.

The protein encoded by this gene is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAMPs are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. In the presence of this (RAMP2) protein, CRLR functions as an adrenomedullin receptor. The RAMP2 protein is involved in core glycosylation and transportation of adrenomedullin receptor to the cell surface.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

RAMP2
Polyclonal
Unconjugated
Ramp2
calcitonin receptor-like receptor activity modifying protein 2; calcitonin-receptor-like receptor activity-modifying protein 2; CRLR activity-modifying protein 2; OTTMUSP00000002615; OTTMUSP00000037624; Ramp2; receptor (calcitonin) activity modifying protein 2; receptor (G protein-coupled) activity modifying protein 2; receptor activity modifying protein 2; receptor activity modifying protein 2 isoform; receptor activity-modifying protein 2; receptor-activity-modifying protein 2; RP23-281C18.6
Sheep
Antigen affinity chromatography
RUO
54409
-20°C, Avoid Freeze/Thaw Cycles
Lyophilized
Flow Cytometry, Western Blot
0.2 mg/mL
PBS with 5% trehalose and No Preservative
Q9WUP0
Ramp2
E. coli-derived recombinant mouse RAMP2 Ser45-Val159.
100 μg
Primary
Mouse
Antibody
IgG
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