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Invitrogen™ RANBP1 Polyclonal Antibody

Description
RANBP1 Polyclonal Antibody for Western Blot, IHC (P)
Ran/TC4-binding protein, RanBP1, interacts specifically with GTP-charged RAN. RANBP1 encodes a 23-kD protein that binds to RAN complexed with GTP but not GDP. RANBP1 does not activate GTPase activity of RAN but does markedly increase GTP hydrolysis by the RanGTPase-activating protein (RanGAP1). The RANBP1 cDNA encodes a 201-amino acid protein that is 92% similar to its mouse homolog. In both mammalian cells and in yeast, RANBP1 acts as a negative regulator of RCC1 by inhibiting RCC1-stimulated guanine nucleotide release from RAN.
Specifications
Specifications
| Antigen | RANBP1 |
| Applications | Immunohistochemistry (Paraffin), Western Blot |
| Classification | Polyclonal |
| Concentration | 1 mg/mL |
| Conjugate | Unconjugated |
| Formulation | TBS with 0.2% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4 |
| Gene | RANBP1 |
| Gene Accession No. | P34022, P43487 |
| Gene Alias | HpaII tiny fragments locus 9A; hpaII tiny fragments locus 9a protein; Htf9a; Htf9-a; Htf9-a/RanBP1; RAN binding protein 1; ran-binding protein 1; RANBP1; RANG; Ran-specific GTPase-activating protein; testis secretory sperm-binding protein Li 221n |
| Gene Symbols | RANBP1 |
| Show More |
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