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RANGAP1 Mouse anti-Human, Clone:4F9E2, Abnova™
Mouse monoclonal antibody raised against recombinant human RANGAP1.
Brand: Abnova MAB16611.100ug
This item is not returnable.
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Description
RanGAP1, is a homodimeric 65-kD polypeptide that specifically induces the GTPase activity of RAN, but not of RAS by over 1,000-fold. RanGAP1 is the immediate antagonist of RCC1, a regulator molecule that keeps RAN in the active, GTP-bound state. The RANGAP1 gene encodes a 587-amino acid polypeptide. The sequence is unrelated to that of GTPase activators for other RAS-related proteins, but is 88% identical to Fug1, the murine homolog of yeast Rna1p. RanGAP1 and RCC1 control RAN-dependent transport between the nucleus and cytoplasm. RanGAP1 is a key regulator of the RAN GTP/GDP cycle. [provided by RefSeq]Specifications
| RANGAP1 | |
| Monoclonal | |
| Unconjugated | |
| ELISA (1:10000) Western Blot (1:500-1:2000) The optimal working dilution should be determined by the end user. |
|
| RANGAP1 | |
| Mouse | |
| 100 μg | |
| Human | |
| Antibody | |
| IgG1 |
| ELISA, Western Blot | |
| 4F9E2 | |
| Ran GTPase activating protein 1 | |
| In PBS (0.05% sodium azide) | |
| Fug1, KIAA1835, MGC20266, SD | |
| Recombinant protein corresponding to amino acid 359-587 of human RANGAP1 from E. coli. | |
| 5905 | |
| Store at 4°C. For long term storage store at -20°C. Aliquot to avoid repeated freezing and thawing. |
|
| Liquid |
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