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Invitrogen™ RAPSN Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA593169
Description
Immunogen sequence: MGQDQTKQQI EKGLQLYQSN QTEKALQVWT KVLEKSSDLM GRFRVLGCLV TAHSEMGRYK EMLKFAVVQI DTARELEDAD FLLESYLNLA RSNEKLCEFH KTISYCKTCL GLPGTRAGAQ LGGQVSLSMG NAFLGLSVFQ KALESFEKAL RYAHNNDDAM LECRVCCSLG SFYAQVKDYE KALFFPCKAA ELVNNYGKGW SLKYRAMSQY HMAVAYRLLG RLGSAMECCE ESMKIALQHG DRPLQALCLL CFADIHRSRG DLELSQLKLH CLSESIYRSK GLQRELRAHV VRFHECVEET ELYCGLCGES IGEKNSRLQA LPCSHIFHLR CLQNNGTRSC PNCRRSSMKP GFV; Positive Samples: B-cell, Mouse skeletal muscle, Mouse brain, Rat skeletal muscle, Rat brain; Cellular Location: Cell junction, Cell membrane, Cytoplasm, Cytoplasmic side, Peripheral membrane protein, cytoskeleton, postsynaptic cell membrane, synapse.
This gene encodes a member of a family of proteins that are receptor associated proteins of the synapse. The encoded protein contains a conserved cAMP-dependent protein kinase phosphorylation site, and plays a critical role in clustering and anchoring nicotinic acetylcholine receptors at synaptic sites by linking the receptors to the underlying postsynaptic cytoskeleton, possibly by direct association with actin or spectrin. Mutations in this gene may play a role in postsynaptic congenital myasthenic syndromes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Specifications
| RAPSN | |
| Polyclonal | |
| Unconjugated | |
| RAPSN | |
| 43 kD receptor-associated protein of the synapse; 43 kda postsynaptic protein; 43 kDa receptor-associated protein of the synapse; 43kDa; 43kDa acetylcholine receptor-associated protein; acetylcholine receptor-associated 43 kda protein; AChR associated protein at synapses; acetylcholine receptor associated protein at synapses; 43kDa protein; likely to cluster nicotinic AChRs; CMS11; CMS1D; CMS1E; CMS4C; FADS; MGC3597; Nraps; Raps; Rapsn; rapsyn; receptor associated protein of the synapse; receptor-associated protein of the synapse; receptor-associated protein of the synapse, 43 kDa; receptor-associated protein of the synapse, 43kD; RING finger protein 205; RNF205; twitch once; two | |
| Rabbit | |
| Affinity Chromatography | |
| RUO | |
| 19400, 362161, 5913 | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Liquid |
| ELISA, Immunohistochemistry (Paraffin), Western Blot | |
| 0.3 mg/mL | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
| P12672, Q13702 | |
| RAPSN | |
| Recombinant protein (or fragment). | |
| 100 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |
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