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Invitrogen™ RASA1 Polyclonal Antibody
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Product Code. 16300295
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Quantity:
100 μL
Unit Size:
100µL
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16300295 100 μL 100µL
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Product Code. 16300295 Supplier Invitrogen™ Supplier No. PA583331

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Description

Rabbit Polyclonal Antibody

Immunogen sequence: LLSSHIPLKG IEPGSLRVRA RYSMEKIMPE EEYSEFKELI LQKELHVVYA LSHVCGQDRT LLASILLRIF LHEKLESLLL CTLNDREISM EDEATT Highest antigen sequence indentity to the following orthologs: Mouse - 99%, Rat - 99%.

TACC1 is located on 8p11 chromosomal region that is amplified in approximately 15% of all breast tumor samples. The short arm of chromosome 8 also contains FGFR1 whose expression is enhanced in most breast cancer tumors. TACC family members, TACC1, TACC2, and TACC3, map very closely to the corresponding FGFR1, FGFR2, FGFR3 genes on chromosomes 4,8, and 10. Subsequently, since they are phylogenetically related, it is proposed that TACC and FGFR have similar roles in cell growth and differentiation. Also, TACC1 contains a conserved C-terminal region as in the Drosophila homolog, D-TACC. It has been shown that D-TACC is necessary for normal spindle function, and the mammalian TACC proteins appears to interact with centrosomes and microtubules in a similar manner.
TRUSTED_SUSTAINABILITY

Specifications

Antigen RASA1
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.05 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene RASA1
Gene Accession No. P20936
Gene Alias CMAVM; CM-AVM; Gap; GAPX; GTPase-activating protein; p120; p120 RAS GTPase activating protein; p120GAP; p120RASGAP; p120-rasGAP; PKWS; Ras GTPase-activating protein 1; ras GTPase-activating protein 1-like protein; Ras p21 protein activator; RAS p21 protein activator (GTPase activating protein RAS p21); RAS p21 protein activator (GTPase activating protein) 1; RAS p21 protein activator 1; Rasa; RASA1; RASGAP; triphosphatase-activating protein; unnamed protein product
Gene Symbols RASA1
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human RASA1. Recombinant protein control fragment (Product #RP-105922).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5921
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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