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Invitrogen™ RASA1 Recombinant Rabbit Monoclonal Antibody (23GB4125), Invitrogen™

Rabbit Recombinant Monoclonal Antibody

Brand:  Invitrogen™ MA553697

 View more versions of this product

Product Code. 30089663

  • € 207.00 / 20µL

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Description

Description

TACC1 is located on 8p11 chromosomal region that is amplified in approximately 15% of all breast tumor samples. The short arm of chromosome 8 also contains FGFR1 whose expression is enhanced in most breast cancer tumors. TACC family members, TACC1, TACC2, and TACC3, map very closely to the corresponding FGFR1, FGFR2, FGFR3 genes on chromosomes 4,8, and 10. Subsequently, since they are phylogenetically related, it is proposed that TACC and FGFR have similar roles in cell growth and differentiation. Also, TACC1 contains a conserved C-terminal region as in the Drosophila homolog, D-TACC. It has been shown that D-TACC is necessary for normal spindle function, and the mammalian TACC proteins appears to interact with centrosomes and microtubules in a similar manner.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

RASA1
Recombinant Monoclonal
Unconjugated
RASA1
CMAVM; CM-AVM; Gap; GAPX; GTPase-activating protein; p120; p120 RAS GTPase activating protein; p120GAP; p120RASGAP; p120-rasGAP; PKWS; Ras GTPase-activating protein 1; ras GTPase-activating protein 1-like protein; Ras p21 protein activator; RAS p21 protein activator (GTPase activating protein RAS p21); RAS p21 protein activator (GTPase activating protein) 1; RAS p21 protein activator 1; Rasa; RASA1; RASGAP; triphosphatase-activating protein; unnamed protein product
Rabbit
Affinity chromatography
RUO
218397, 25676, 5921
-20°C
Liquid
Western Blot, Immunocytochemistry
23GB4125
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
P20936, P50904
RASA1
A synthesized peptide derived from human RASA1 (250-300AA).
20 μL
Primary
Human, Mouse, Rat
Antibody
IgG
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