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Invitrogen™ RASD2 Polyclonal Antibody
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Product Code. 12898612
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Quantity:
100 μg
Unit Size:
100µg
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12898612 100 μg 100µg
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Product Code. 12898612 Supplier Invitrogen™ Supplier No. PA520438

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Description

Rabbit Polyclonal Antibody

A suggested positive control is human colon tissue lysate. PA5-20438 can be used with blocking peptide PEP-0555.

Rhes, also known as tumor endothelial marker 2 (TEM2), is a small GTP-binding protein that is predominantly expressed in the striatal region of the brain. This protein belongs to the RASD subfamily of Ras-related GTP-binding protein superfamily and is thought to play a role in the normal development and function of the brain as mice lacking this gene showed increased anxiety levels and motor coordination deficits. Rhes was identified as TEM2 through analysis of genes whose expression was upregulated in tumor endothelium. Tumor endothelial markers are significantly up-regulated during angiogenesis and neoangiogenesis that are crucial for the growth of solid tumors. TEMs localized on the cell surface and conserved across species are of particular interest for future development of anti-angiogenic therapies.
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Specifications

Antigen RASD2
Applications Immunohistochemistry, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene RASD2
Gene Accession No. P63032, P63033, Q96D21
Gene Alias 4930526B11Rik; AU045414; GTP-binding protein Rhes; MGC:4834; Ras homolog enriched in striatum; RASD family member 2; RASD family, member 2; Rasd2; Rhes; SE6C; TEM2; TEM-2; Tumor endothelial marker 2
Gene Symbols RASD2
Host Species Rabbit
Immunogen A 15 amino acid peptide near the carboxy terminus of the human TEM2.
Purification Method Antigen Affinity Chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 171099, 23551, 75141
Target Species Human, Mouse, Rat
Content And Storage Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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