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Invitrogen™ RASGRF1 Polyclonal Antibody

Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA578412
This item is not returnable.
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Description
Positive Control: mouse brain, rat brain Predicted reactivity: Rat (100%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
RASGRF1 is a guanine nucleotide exchange factor (GEF) similar to the Saccharomyces cerevisiae CDC25 gene product. Functional analysis has demonstrated that this protein stimulates the dissociation of GDP from RAS protein. Studies of the similar gene in mouse suggested that the Ras-GEF activity of this protein in brain can be activated by Ca2+ influx, muscarinic receptors, and G protein beta-gamma subunit. Mouse studies also indicated that the Ras-GEF signaling pathway mediated by this protein may be important for long-term memory.
Specifications
| RASGRF1 | |
| Polyclonal | |
| Unconjugated | |
| RASGRF1 | |
| AI844718; ASPP1; Cdc25; CDC25L; CDC25Mm; Gnrp; GRF1; GRF55; Grfbeta; guanine nucleotide exchange factor; guanine nucleotide-releasing factor 1; guanine nucleotide-releasing factor, 55 kD; guanine nucleotide-releasing protein; H-GRF55; KIAA0771; P140 Ras-GRF; p190; P190-A; p190RhoGEF; PP13187; PPP1R13B; Ras guanine release factor beta; Ras protein specific guanine nucleotide releasing factor 1; RAS protein-specific guanine nucleotide-releasing factor 1; Rasgrf1; ras-GRF1; Ras-specific guanine nucleotide-releasing factor 1; Ras-specific guanine nucleotide-releasing factor, CDC25 homolog; ras-specific nucleotide exchange factor CDC25 | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 192213, 19417 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Immunohistochemistry (Paraffin), Western Blot | |
| 1 mg/mL | |
| PBS with 20% glycerol and 0.025% ProClin 300; pH 7 | |
| P27671, P28818 | |
| RASGRF1 | |
| Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of Rat RASGRF1. The exact sequence is proprietary. | |
| 100 μL | |
| Primary | |
| Mouse, Rat | |
| Antibody | |
| IgG |
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