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RASSF1 Monoclonal Antibody (OTI8E2), TrueMAB™, OriGene

Product Code. 17597011
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100 μL
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100µL
30µL
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17597011 100 μL 100µL
17517021 30 μL 30µL
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Product Code. 17597011 Supplier Origene Technologies Supplier No. TA502486

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Description

Mouse Monoclonal Antibody

This gene encodes a protein similar to the RAS effector proteins. Loss or altered expression of this gene has been associated with the pathogenesis of a variety of cancers, which suggests the tumor suppressor function of this gene. The inactivation of this gene was found to be correlated with the hypermethylation of its CpG-island promoter region. The encoded protein was found to interact with DNA repair protein XPA. The protein was also shown to inhibit the accumulation of cyclin D1, and thus induce cell cycle arrest. Seven alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

Specifications

Antigen RASSF1
Applications Immunocytochemistry, Immunofluorescence, Western Blot
Classification Monoclonal
Clone OTI8E2
Concentration 0.87 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene RASSF1
Gene Accession No. Q9NS23
Gene Alias IGKV1/OR-2, IGKV1OR2-PENDING
Gene Symbols RASSF1
Host Species Mouse
Immunogen Full length human recombit protein of human RASSF1 produced in E.coli.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11186
Target Species Human
Content And Storage -20° C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG2b
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