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PRKAR2A, Rat, Polyclonal Antibody, Abnova™

Product Code. 16005227
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Quantity:
100 μL
Unit Size:
100µL
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16005227 100 μL 100µL
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Product Code. 16005227 Supplier Abnova Supplier No. PAB24989.100uL

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Description

Rabbit polyclonal antibody raised against synthetic peptide of PRKAR2A.

cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation of different target proteins. The inactive kinase holoenzyme is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. The protein encoded by this gene is one of the regulatory subunits. This subunit can be phosphorylated by the activated catalytic subunit. It may interact with various A-kinase anchoring proteins and determine the subcellular localization of cAMP-dependent protein kinase. This subunit has been shown to regulate protein transport from endosomes to the Golgi apparatus and further to the endoplasmic reticulum (ER). [provided by RefSeq

Specifications

Antigen PRKAR2A
Applications Immunofluorescence, Immunohistochemistry, Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic peptide of PRKAR2A.
Dilution Western Blot (1:500-1:1000) Immunohistochemistry (1:50-1:200) The optimal working dilution should be determined by the end user.
Formulation In PBS, pH 7.2 (0.05% sodium azide)
Gene PRKAR2A
Gene Alias MGC3606/PKR2/PRKAR2
Gene Symbols PRKAR2A
Host Species Rat
Immunogen A synthetic peptide corresponding to PRKAR2A.
Purification Method Antigen affinity purification
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5576
Test Specificity PRKAR2A polyclonal antibody detects endogenous levels of PRKAR2A protein.
Target Species Human
Content And Storage Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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