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Description
The U4-1374 monoclonal antibody specifically recognizes the Zinc finger and BTB domain containing 46 (Zbtb46) transcription factor, which is also known as BTB-ZF protein expressed in effector lymphocytes (BZEL), or BTB (POZ) domain containing 4 (Btbd4). Zbtb46 is a transcription factor that is selectively expressed by conventional dendritic cells (cDC; also known as classical dendritic cells) and their committed progenitors. It is not expressed by plasmacytoid DCs (pDC), monocytes, macrophages, or other lymphoid or myeloid lineages. Although Zbtb46 is not required for cDC development, it represses the expression of alternative myeloid growth factor receptors and thereby enforces cDC lineage restriction.
Specifications
| Zbtb46 | |
| Monoclonal | |
| 0.2mg/mL | |
| ZBT46; BZEL ; Btbd4; Zinc finger and BTB domain containing 46 | |
| Rat | |
| Affinity Purified | |
| RUO | |
| Mouse | |
| IgG1 κ |
| Flow Cytometry, Immunocytochemistry | |
| U4-1374 | |
| PE | |
| Aqueous buffered solution containing ≤0.09% sodium azide. | |
| Mouse Zbtb46 Recombinant Protein | |
| 50 μg | |
| Primary | |
| Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. |
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