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Gibco™ Rat CXCL1 (GRO alpha) Recombinant Protein

Product Code. 10641884
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Quantity:
25 μg
Unit Size:
Each
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Product Code. 10641884

Brand: Gibco™ PRC1066

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Description

Recombinant Protein

Carrier-Free Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Recombinant rat GRO should be reconstituted in sterile, distilled water to a concentration of 0.1-1.0 mg/mL. Recombinant rat GRO is also soluble in most buffered solutions. Further dilutions should be made in buffered solution with carrier protein such as PBS with 1% BSA. Storage: This lyophilized preparation is stable at 2°C to 8°C, but should be kept at -20°C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2°C to 8°C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20°C. Avoid repeated freeze/thaw cycles.

CXCL1, CXCL2, and CXCL3, also known respectively as GRO alpha, GRO beta (MIP-2 alpha) and GRO gamma (MIP-2 beta), are members of the CXC subfamily of chemokines. Mature CXCL1/2/3 proteins bind with high affinity to the IL-8 receptor type B and are potent neutrophil attractants and activators. In vitro, the processed forms GRO-alpha(4-73), GRO-alpha(5-73) and GRO-alpha(6-73) show a 30-fold higher chemotactic activity.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number P14095
For Use With (Application) Bioactivity
Formulation Protein with no preservative
Gene ID (Entrez) 81503
Molecular Weight (g/mol) 7.8 kDa
Name Rat CXCL1 (GRO alpha)
Purification Method Purified
Quantity 25 μg
Storage Requirements 4°C
Regulatory Status RUO
Endotoxin Concentration <0.1 ng/μg
Gene Alias alpha-chemokine; C Cmotif chemokine; C X C motif chemokine; CC motif chemokine; CCmotif chemokine; chemokine (C-X-C motif) ligand 1; chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha); Cinc1; CINC-1; CXC; CXC motif chemokine; C-X-C motif chemokine 1; C-X-C motif chemokine ligand 1; CXCL; CXCL1; CXCL-1; Cytokine-induced neutrophil chemoattractant 1; fibroblast secretory protein; Fsp; Gro; GRO a; GRO α; Gro1; GRO1 oncogene; GRO1 oncogene (melanoma growth stimulating activity, alpha); GRO1 oncogene (melanoma growth-stimulating activity); GROa; GROalpha; GRO-alpha(1-73); GRO-alpha(4-73); GRO-alpha(5-73); GRO-alpha(6-73); Growth-regulated alpha protein; GROα; Hematopoietic synergistic factor; HSF; KC; KC(5-72); KC/GR)-alpha; KC/GRO-alpha; KC-T; melanoma growth stimulating activity, alpha; Melanoma growth stimulatory activity; melanoma growth stimulatory activity alpha; MGSA; MGSA alpha; MGSA-a; N51; NAP3; NAP-3; Neutrophil-activating protein 3; platelet-derived growth factor-inducible protein KC; SCYB1; secretory protein N51
Common Name CXCL1 (GRO alpha)
Gene Symbol Cxcl1
Biological Activity ED50 = 10 - 100 ng/mL; determined by the dose-dependent chemotaxis of rat neutrophils.
Product Type Protein
Conjugate Unconjugated
Species Rat
Recombinant Recombinant
Sequence APVANELRCQ CLQTVAGIHF KNIQSLKVMP PGPHCTQTEV IATLKNGREA CLDPEAPMVQ KIVQKMLKGV PK
Content And Storage 4°C
Classification Carrier-Free
Activity ED50 = 10 - 100 ng/mL; determined by the dose-dependent chemotaxis of rat neutrophils.
Endotoxin Level <0.1 ng/μg
Shipping Condition Approved for shipment on Wet or Dry Ice
Expression System E. coli
Protein Family Chemokines & Receptors
Protein Form Recombinant, Ligand
Form Lyophilized
Protein Subtype GRO⁄KC⁄CINC Chemokines
Research Category Cell Cycle & Proliferation, Oncology, Inflammation, Stem Cell Research, Neurobiology, Angiogenesis
Product Line Gibco
Purity or Quality Grade >98% by SDS-PAGE
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