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Invitrogen™ Rat PDGFRA (CD140a) Fc Chimera Recombinant Protein

Product Code. 17925501
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Quantity:
100 μg
Unit Size:
100µg
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Product Code. 17925501

Brand: Invitrogen™ RP88273

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This item is not returnable. View return policy

Description

Recombinant Protein

It is recommended that the protein be aliquoted for optimal storage. It is recommended that sterile water (400 μL) be added to the vial to prepare a stock solution of 0.25 mg/mL. Concentration is measured by UV.

PDGFRA is a cell surface receptor tyrosine kinase which binds members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies in knockout mice, where homozygosity is lethal, indicate that the alpha form of the platelet-derived growth factor receptor is particularly important for kidney development since mice heterozygous for the receptor exhibit defective kidney phenotypes.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number P20786
For Use With (Application) Control, Neutralization
Format Lyophilized
Formulation PBS with 0.01% mannitol, 5-8% trehalose, 0.01% Tween 80 and no preservative; pH 7.4
Gene ID (Entrez) 25267
Molecular Weight (g/mol) 112-120 kDa
Name Rat PDGFRA (CD140a) Fc Chimera
pH Range 7.4
Purification Method Purified
Quantity 100 μg
Storage Requirements -20°C, Avoid Freeze/Thaw Cycles
Regulatory Status RUO
Endotoxin Concentration <1.0 EU/μg
Gene Alias AI115593; alpha platelet-derived growth factor receptor; Alpha platelet-derived growth factor receptor precursor (PDGF-R-alpha); alpha-type platelet-derived growth factor receptor; APDGFR; CD140 antigen-like family member A; CD140A; CD140a antigen; GAS9; MGC74795; OTTHUMP00000218656; PDGF A-chain; PDGF alpha chain; PDGF Receptor alpha; PDGF subunit A; PDGF-1; PDGFACE; PDGFR2; Pdgfr-2; PDGFRA; pdgfr-a; PDGFRA/BCR fusion; PDGF-R-alpha; PDGFR-alpha; platelet derived growth factor receptor alpha; platelet derived growth factor receptor, alpha polypeptide; platelet-derived growth factor alpha receptor; Platelet-derived growth factor receptor 2; platelet-derived growth factor receptor alpha; platelet-derived growth factor receptor, alpha polypeptide; rearranged-in-hypereosinophilia-platelet derived growth factor receptor alpha fusion protein; RHEPDGFRA
Common Name PDGFRA (CD140a)
Gene Symbol PDGFRA
Product Type Protein
Conjugate Unconjugated
Recombinant Recombinant
Protein Tag Fc-tag
Sequence Rat PDGFRA, amino acids Met1-Glu523 (Accession # G3V6A0) with a C-terminal human IgG1 Fc region
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Expression System HEK293 cells
Form Lyophilized
Purity or Quality Grade >95% as determined by SDS-PAGE.
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