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RB1 Monoclonal Antibody (OTI11C10), TrueMAB™, OriGene
Mouse Monoclonal Antibody
Brand: Origene Technologies TA805623
This item is not returnable.
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Description
Rb is a tumor suppressor nuclear phosphoprotein capable of binding to DNA. It is phosphorylated on serine and threonine, but not on tyrosine residues. It forms a complex with SV40 large T antigen, adenovirus E1A, and human papilloma virus-16 E. Rb protein may act by regulating transcription and loss of its function leads to uncontrolled cell growth. Aberrations in the RB gene have been implicated in cancers of breast, colon, prostate, kidney, nasopharynx, and leukemia.Specifications
| RB1 | |
| Monoclonal | |
| Unconjugated | |
| RB1 | |
| OSRC, PPP1R130, RB, p105-Rb, pRb, pp110 | |
| Mouse | |
| Affinity Chromatography | |
| RUO | |
| 5925 | |
| -20° C, Avoid Freeze/Thaw Cycles | |
| Liquid |
| Immunohistochemistry (Paraffin), Western Blot | |
| OTI11C10 | |
| PBS with 1% BSA, 50% glycerol and 0.02% sodium azide | |
| P06400 | |
| RB1 | |
| Human recombit protein fragment corresponding to amino acids 309-590 of human RB1 produced in E.coli. | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG2b |
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