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Invitrogen™ RBM15 Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA592321
This item is not returnable.
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Description
Immunogen sequence: EHRYQQQYLQ PLPLTHYELV TDAFGHRAPD PLRGARDRTP PLLYRDRDRD LYPDSDWVPP PPPVRERSTR TAATSVPAYE PLDSLDRRRD GWSLDRDRGD RDLPSSRDQP RKRRLPEESG GRHLDRSPES DRPRKRHCAP SPDRSPELSS SRDRYNSDND RSSRLLLERP SPIRDRRGSL EKSQGDKRDR KNSASAERDR KHRTTAPTEG KSPLKKEDRS DGSAPSTSTA SSKLKSPSQK QDGGTAPVAS A; Positive Samples: HL-60, HepG2, 293T, Jurkat, Mouse thymus, Mouse spleen; Cellular Location: Nucleus, Nucleus membrane, Nucleus speckle, Peripheral membrane protein, nucleoplasm.
May function as an mRNA export factor, stimulating export and expression of RTE-containing mRNAs which are present in many retrotransposons that require to be exported prior to splicing. High affinity binding of pre-mRNA to RBM15 may allow targeting of the mRNP to the export helicase DBP5 in a manner that is independent of splicing-mediated NXF1 deposition, resulting in export prior to splicing. May be implicated in HOX gene regulation.
Specifications
| RBM15 | |
| Polyclonal | |
| Unconjugated | |
| RBM15 | |
| C230088J01Rik; Kiaa4257; mKIAA1438; one twenty two protein; one twenty-two; one-twenty two protein 1; OTT; OTT1; putative RNA-binding protein 15; RBM15; RNA binding motif protein 15; RNA-binding motif protein 15; RNA-binding protein 15; SPEN | |
| Rabbit | |
| Affinity chromatography | |
| RUO | |
| 229700, 64783 | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Liquid |
| ELISA, Immunohistochemistry (Paraffin), Western Blot | |
| 0.38 mg/mL | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
| Q96T37 | |
| RBM15 | |
| Recombinant fusion protein containing a sequence corresponding to amino acids 530-780 of human RBM15 (NP_0011884741). | |
| 100 μL | |
| Primary | |
| Human, Mouse | |
| Antibody | |
| IgG |
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