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R&D Systems™ Recombinant Cynomolgus Lymphotoxin beta R/TNFRSF3 Fc, CF
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Quantity:
50 μg
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50µg
Description
Measured by its ability to inhibit Lymphotoxin alpha 1/beta 2-induced IL-8 secretion in A375 human melanoma cells. Degli-Esposti, M. et al. (1997) J. Immunol. 158:1756. The ED50 for this effect is 30.0-180 ng/mL in the presence of 100 ng/mL Recombinant Human Lymphotoxin alpha 1/beta 2 (Catalog # 8884-LY ).
Specifications
Specifications
| Accession Number | XP_005569951.1 |
| For Use With (Application) | Bioactivity |
| Formulation | Lyophilized from a 0.2 μm filtered solution in PBS. |
| Gene ID (Entrez) | 4055 |
| Molecular Weight (g/mol) | M.W. (Observed): 57-68 kDa, under reducing conditions, M.W. (Theoretical): 48 kDa |
| Quantity | 50 μg |
| Source | Chinese Hamster Ovary cell line, CHO-derived cynomolgus monkey Lymphotoxin beta R/TNFRSF3 protein Cynomolgus Monkey Lymphotoxin beta R/TNFRSF3 (Ser28-Met227) (N-terminus) Accession # XP_005569951.1 IEGRMD Human IgG1 (Pro100-Lys330) (C-terminus) |
| Storage Requirements | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20°C to -70°C as supplied. 1 month, 2°C to 8°C under sterile conditions after reconstitution. 3 months, -20°C to -70°C under sterile conditions after reconstitution. |
| Endotoxin Concentration | <0.10 EU per 1 μg of the protein by the LAL method. |
| Gene Alias | CD18, D12S370, ltbetar, LT-BETA-R, LTBR, lymphotoxin B receptor, lymphotoxin beta receptor (TNFR superfamily, member 3), Lymphotoxin-beta receptor, LymphotoxinbR, TNF RIII, TNF Rrp, TNFCRTNF-RIII, TNFR superfamily, member 3, TNFR2-RP, TNFR3, TNF-R-III, TNFR-RP, TNFRSF3, TNFRSF3TNFR-III, Tumor necrosis factor C receptor, Tumor necrosis factor receptor 2-related protein, tumor necrosis factor receptor superfamily member 3, tumor necrosis factor receptor superfamily, member 3, Tumor necrosis factor receptor type III |
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