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R&D Systems™ Recombinant Human Noggin GMP Protein, CF
Description
Measured by its ability to inhibit BMP-4-induced alkaline phosphatase production by ATDC5 mouse chondrogenic cells. The ED50 for this effect is 0.0200-0.240 μg/mL.
Specifications
Specifications
| Accession Number | Q13253.1 |
| For Use With (Application) | Bioactivity |
| Formulation | Lyophilized from a 0.2 μm filtered solution in Sodium Acetate with Trehalose. |
| Gene ID (Entrez) | 9241 |
| Molecular Weight (g/mol) | Observed: 27 kDa, under reducing conditions., Theroretical: 23 kDa (monomer) |
| Quantity | 1 mg |
| Source | E. coli-derived human Noggin protein Gln28 - Cys232 with an N-terminal Met Produced using non-animal reagents in an animal-free laboratory. Manufactured and tested under cGMP guidelines. |
| Storage Requirements | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. A minimum of 12 months when stored at ≤-20°C as supplied. Refer to lot specific COA for the Use by Date. 1 month, 2°C to 8°C under sterile conditions after reconstitution. 3 months, ≤-20°C under sterile conditions after reconstitution. |
| Endotoxin Concentration | <0.10 EU per 1 μg of the protein by the LAL method. |
| Gene Alias | NOG, noggin, SYM1, symphalangism 1 (proximal), synostoses (multiple) syndrome 1, SYNS1, SYNS1A |
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