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R&D Systems™ Recombinant Human PVRIG Fc Chimera Protein

Product Code. 18759057
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Quantity:
50 μg
Unit Size:
50µg
This item is not returnable. View return policy

Product Code. 18759057

Brand: R&D Systems™ 9365PV050

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This item is not returnable. View return policy

Description

Expressed in lymphocytes, such as T cells and NK cells, but not in monocyte derived dendritic cells.

Human PVRIG (poliovirus receptor related immunoglobulin domain-containing protein), also known as CD112 receptor (CD112R), is approximately 34 kDa single transmembrane protein in the poliovirus receptor-like protein (PVR) family. It is composed of single extracellular IgV domain, one transmembrane domain, and long intracellular domain. The intracellular domain contains two tyrosine residues, one within an ITIM-like motif that is potential docking site for phosphatases. Reconstitute at 500μg/mL in PBS

Storage:

Store the unopened product at −20 to −70°C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Order Info

Ships at ambient temperature.

TRUSTED_SUSTAINABILITY

Specifications

Accession Number Q6DKI7
For Use With (Application) Bioactivity
Formulation Lyophilized from a 0.2 μm filtered solution in MOPS, NaCl and PEG with Trehalose.
Gene ID (Entrez) 79037
Molecular Weight (g/mol) 40 kDa
Quantity 50 μg
Source Human embryonic kidney cell, HEK293-derived human PVRIG protein, (N-terminus) Human PVRIG (Thr41 & Glu43-Leu172) Accession # Q6DKI7 IEGRMD Human IgG1 (Pro100-Lys330) (C-terminus)
Storage Requirements Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70°C as supplied. 1 month, 2 to 8°C under sterile conditions after reconstitution. 3 months, -20 to -70°C under sterile conditions after reconstitution.
Regulatory Status RUO
Structural Form Disulfide-linked homodimer
Endotoxin Concentration <0.10 EU per 1 μg of the protein by the LAL method.
Biological Activity 0.4 to 2.4μg/mL
Product Type Recombinant protein
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Reconstitution Reconstitute at 250 μg/mL in sterile water.
Purity or Quality Grade >95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie™ Blue Staining.
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For Research Use Only.

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