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R&D Systems™ Recombinant Mouse VSIG4 Fc Chimera Protein

Product Code. 18166550
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Quantity:
50 μg
Unit Size:
50µg
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Product Code. 18166550

Brand: R&D Systems™ 4674VS050

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429.60 EUR valid until 2025-12-16
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This item is not returnable. View return policy

Description

Extensive quality control produces industry leading bioactivity and lot-to-lot consistency that instills confidence in results and ensures reproducibility.

Measured by its ability to inhibit anti-CD3-induced proliferation of splenic T lymphocytes. Vogt, L. et al. (2006) J. Clin. Invest. 116:2817. The presence of immobilized Recombinant Mouse VSIG4 Fc Chimera inhibited the anti-CD3 response by =50%. The ED50 for this effect is 1.25-5 μg/mL.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number NP_808457
For Use With (Application) Bioactivity
Formulation Lyophilized from a 0.2 μm filtered solution in PBS.
Gene ID (Entrez) 11326
Molecular Weight (g/mol) M.W. (Observed): 60-65 kDa, reducing conditions; M.W. (theoretical): 46 kDa (monomer)
Name VSIG4 Fc Chimera
Quantity 50 μg
Source Mouse myeloma cell line, NS0-derived mouse VSIG4 protein Mouse VSIG4 (His20-Pro187) (N-terminus) Accession # NP_808457 IEGRMDP Mouse IgG2A (Glu98-Lys330) (C-terminus)
Storage Requirements Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20°C to -70°C as supplied. 1 month, 2°C to 8°C under sterile conditions after reconstitution. 3 months, -20°C to -70°C under sterile conditions after reconstitution.
Structural Form Disulfide-linked homodimer
Endotoxin Concentration <1.0 EU / 1 μg of the protein by the LAL method.
Gene Symbol Vsig4
Conjugate Unconjugated
Recombinant Recombinant
Reconstitution Reconstitute at 200 μg/mL in sterile PBS.
Purity or Quality Grade >90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie™ Blue Staining.
Protein VSIG4
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