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RET Monoclonal Antibody (OTI5C5), TrueMAB™, OriGene

Mouse Monoclonal Antibody

Brand:  Origene Technologies TA805767

Encompass_Preferred

 View more versions of this product

Product Code. 17515763

  • € 540.87 / 100µL

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This item is not returnable. View return policy

Description

Description

RET is a member of the cadherin superfamily, encodes one of the receptor tyrosine kinases which are cell-surface molecules that transduce signals for cell growth and differentiation. RET plays a crucial role in neural crest development, can undergo oncogenic activation in vivo and in vitro by cytogenetic rearrangement. Mutations in the RET gene are associated with the disorders multiple endocrine neoplasia, type IIA, multiple endocrine neoplasia, type IIB, Hirschsprung disease, and medullary thyroid carcinoma. Two transcript variants encoding different isoforms have been found for the RET gene. Additional transcript variants have been described for RET but their biological validity has not been confirmed.
Specifications

Specifications

RET
Monoclonal
1 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
P07949
RET
Human recombit protein fragment corresponding to amino acids 713-1017 of human RET produced in E.coli.
100 μL
Primary
Human
Antibody
IgG1
Immunohistochemistry (Paraffin), Western Blot
OTI5C5
Unconjugated
RET
CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET-ELE1
Mouse
Affinity Chromatography
RUO
5979
-20° C, Avoid Freeze/Thaw Cycles
Liquid
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