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RGS18 Monoclonal Antibody (OTI8C8), TrueMAB™, OriGene
Mouse Monoclonal Antibody
Brand: Origene Technologies TA812073
This item is not returnable.
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Description
RGS signaling proteins are highly diverse and multifunctional proteins that act as inhibitors of G-protein signaling.RGS18, a 235 A.A protein, is the smallest member of this family. It is predomitly expressed in immune tissues and is characterized by the presence of a conserved 120A.A RGS domain. It is found to be expressed in lymphocytes, megakaryocytes and platelets and might play an important role in regulating G-protein mediated signaling in lungs and immune system. It specifically binds to GTP-bound G-alpha subunits and acts as a GAP protein, thus inhibiting G-alpha mediated signaling. It blocks MAP-Kinase activity and cAMP generation induced by G-alpha-i or G-alpha-q-coupled receptors. This protein is thought to play an important role in proliferation, differentiation and migration of megakaryocytes and platelets.Specifications
| RGS18 | |
| Monoclonal | |
| 1 mg/mL | |
| PBS with 1% BSA, 50% glycerol and 0.02% sodium azide | |
| Q9NS28 | |
| RGS18 | |
| Full length human recombit protein of human RGS18 produced in E.coli. | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG1 |
| Western Blot | |
| OTI8C8 | |
| Unconjugated | |
| RGS18 | |
| RGS13 | |
| Mouse | |
| Affinity Chromatography | |
| RUO | |
| 64407 | |
| -20° C, Avoid Freeze/Thaw Cycles | |
| Liquid |
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