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Invitrogen™ RGS18 Polyclonal Antibody
Goat Polyclonal Antibody
Brand: Invitrogen™ PA518279
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Description
This antibody is tested in Peptide ELISA: antibody detection limit dilution 16,000.
This gene encodes a member of the regulator of G-protein signaling family. This protein is contains a conserved, 120 amino acid motif called the RGS domain. The protein attenuates the signaling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.
Specifications
| RGS18 | |
| Polyclonal | |
| Unconjugated | |
| RGS18 | |
| regulator of G-protein signaling 18; regulator of G-protein signalling 13; regulator of G-protein signalling 18; RGS13; RGS18; RP11-142L4.1 | |
| Goat | |
| Ammonium sulfate precipitation | |
| RUO | |
| 64407 | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Liquid |
| Immunohistochemistry (Paraffin), Western Blot | |
| 0.5 mg/mL | |
| TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3 | |
| Q9NS28 | |
| RGS18 | |
| Synthetic peptide sequence (CNEFQDVQSDVAIWL) corresponding to the C-terminus amino acids of RGS18 (aa 221-235). | |
| 100 μg | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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