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Invitrogen™ RGS21 Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA5104094
This item is not returnable.
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Description
Antibody detects endogenous levels of total RGS21.
Regulator of G-protein signaling (RGS) proteins contain an 120 amino acid conserved domain, termed the RGS domain, that acts as a GTPase-activating protein that acts to reduce the signal transmitted by the receptor-activated G-alpha subunit. RGS21 is a recently identified member of this family that has been reported to be selectively expressed in subpopulations of taste bud cells and co-expressed with bitter and sweet transduction components such as alpha-gusticin, phospholipase Cbeta2, T1R2/T1R3 sweet taste receptors and T2R bitter taste receptors. Other reports indicate that RGS21 is more widely expressed. Binding assays demonstrate that RGS21 binds alpha-gusticin in a conformation-dependent manner and may do the same with T1R receptors, suggesting that RGS21 may play a role in sweet and bitter taste transduction processes.
Specifications
| RGS21 | |
| Polyclonal | |
| Unconjugated | |
| RGS21 | |
| EG624910; regulator of G-protein signaling 21; regulator of G-protein signalling 21; RGS21 | |
| Rabbit | |
| Affinity chromatography | |
| RUO | |
| 100361166, 431704, 624910 | |
| -20°C | |
| Liquid |
| Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry | |
| 1 mg/mL | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 | |
| Q2M5E4 | |
| RGS21 | |
| A synthesized peptide derived from human RGS21(Accession Q2M5E4), corresponding to amino acid residues M1-E49. | |
| 100 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |
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