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Invitrogen™ RHEB Monoclonal Antibody (GT39810)
Description
Positive Control: SK-N-SH Predicted Reactivity: Mouse (98%), Rat (99%), Zebrafish (90%), Xenopus laevis (91%), Pig (99%), Sheep (99%), Rhesus Monkey (100%), Bovine (98%) Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Rheb encodes a member of the small GTPase superfamily and encodes a lipid-anchored, cell membrane protein with five repeats of the RAS-related GTP-binding region. This protein is vital in regulation of growth and cell cycle progression due to its role in the insulin/TOR/S6K signaling pathway. The protein has GTPase activity and shuttles between a GDP-bound form and a GTP-bound form, and farnesylation of the protein is required for this activity. Three pseudogenes have been mapped, two on chromosome 10 and one on chromosome 22.
Specifications
Specifications
| Antigen | RHEB |
| Applications | Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry |
| Classification | Monoclonal |
| Clone | GT39810 |
| Concentration | 1 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with no preservative |
| Gene | RHEB |
| Gene Accession No. | Q15382, Q62639, Q921J2 |
| Gene Alias | GTP-binding protein Rheb; Ras homolog enriched in brain; Ras homolog enriched in brain 2; RAS-homolog enriched in brain; RHEB; Rheb1; RHEB2 |
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