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Invitrogen™ RhoB VHH-8His-Cys-tag Recombinant Alpaca Monoclonal Antibody (SAA1319)
Description
RhoB VHH-8His-Cys-tag Recombinant Monoclonal Antibody for SPR, ICC/IF, IP
Rho-related GTP-binding protein (RhoB) mediates apoptosis in neoplastically transformed cells after DNA damage. While not essential for development, it does affect cell adhesion and growth factor signaling in transformed cells. RhoB targets PKN1 to endosomes and is involved in trafficking of the EGF receptor from late endosomes to lysosomes. Also required for stability and nuclear trafficking of AKT1/AKT which promotes endothelial cell survival during vascular development. Serves as a tumor supressor - deletion of RhoB causes tumor formation.
Specifications
Specifications
| Antigen | RhoB VHH-8His-Cys-tag |
| Applications | Immunoprecipitation, Immunocytochemistry, Surface Plasmon Resonance |
| Classification | Recombinant Monoclonal |
| Clone | SAA1319 |
| Concentration | 1 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with no preservative |
| Gene | RHOB |
| Gene Accession No. | P62745 |
| Gene Alias | AA017882; Aplysia RAS-related homolog 6; aplysia ras-related homolog B; Arh6; Arhb; h6; MST081; MSTP081; oncogene RHO H6; ras homolog B; ras homolog family member B; ras homolog gene family, member AB; ras homolog gene family, member B; Rho; rho cDNA clone 6; rhoB; RHOH6; Rho-related GTP-binding protein RhoB |
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