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  7. Rifabutin, 98%, Thermo Scientific Chemicals

Rifabutin, 98%, Thermo Scientific Chemicals

Codice prodotto. 15721769 Sfoglia Tutto Thermo Scientific Chemicals Prodotti
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Codice prodotto. 15721769 Fornitore Thermo Scientific Acros N. del fornitore 461210010
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Descrizione

Rifabutin, CAS # 72559-06-09, is a broad-spectrum antibiotic with activity against mycobacteria, gram-positive and gram-negative bacteria.

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

  • Rifabutin is a compound with antibacterial activity most commonly used against Mycobacterium tuberculosis
  • Rifabutin is a derivative of Rifamycin S that acts through blocking RNA polymerase subunit beta (RpoB)
  • Rifabutin is an inducer as well as a substrate of CYP3A, a cytochrome P450 enzyme

Applications

  • Rifabutin may be used in pharmacokinetic laboratory studies and high-throughput drug screens
  • May be used in laboratory studies to determine drug resistance mutations present in Mycobacterium tuberculosis strains
TRUSTED_SUSTAINABILITY

Identificatori chimici

CAS 72559-06-9
Molecular Formula C46H62N4O11
Molecular Weight (g/mol) 847.02
MDL Number MFCD00866816
InChI Key ATEBXHFBFRCZMA-VXTBVIBXSA-N
Synonym rifabutin, ansamycin, rifabutine, mycobutin, ansatipine, ansatipin, alfacid, rifabutina, rifabutinum, antibiotic lm 427
PubChem CID 57448257
IUPAC Name (7S,9E,11S,12R,13S,14R,15R,16R,17S,18S,19E,21Z)-2,15,17-trihydroxy-11-methoxy-3,7,12,14,16,18,22-heptamethyl-1'-(2-methylpropyl)-6,23,32-trioxo-8,33-dioxa-24,27,29-triazaspiro[pentacyclo[23.6.1.1⁴,⁷.0⁵,³¹.0²⁶,³⁰]tritriacontane-28,4'-piperidin]-1,3,5(31),9,19,21,25,29-octaen-13-yl acetate
SMILES CO[C@H]1\C=C\O[C@@]2(C)OC3=C(C)C(O)=C4C(=O)C(NC(=O)\C(C)=C/C=C/[C@H](C)[C@H](O)[C@@H](C)[C@@H](O)[C@@H](C)[C@H](OC(C)=O)[C@@H]1C)=C1NC5(CCN(CC(C)C)CC5)N=C1C4=C3C2=O

Specifica

Assay Percent Range 97.5% min. (HPLC)
Packaging Glass Bottle
Quantity 1 g
Formula Weight 847
Percent Purity 98%
Chemical Name or Material Rifabutin

Sicurezza e movimentazione

compliance-icons
Identificativo prodotto
  • Rifabutin
 Avvertenza
  • Warning
 Categoria di pericolo
  • Serious eye damage/eye irritation Category 2
  • Skin corrosion/irritation Category 2
  • Specific target organ toxicity Category 3
 Indicazioni di pericolo
  • H315-Causes skin irritation.
  • H319-Causes serious eye irritation.
  • H335-May cause respiratory irritation.
 Consigli di prudenza
  • P280-Wear protective gloves/protective clothing/eye protection/face protection.
  • P302+P352-IF ON SKIN: Wash with plenty of water/soap.
  • P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
  • P312-Call a POISON CENTER/doctor/if you feel unwell.
  • P332+P313-If skin irritation occurs: Get medical advice/attention.
  • P337+P313-If eye irritation persists: Get medical advice/attention.
 Informazioni supplementari
  • MIXTURE LIST-Contain: Rifabutin
SDS

RUO – Research Use Only

Titolo del prodotto
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