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Invitrogen™ RIM1 Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA5117424
This item is not returnable.
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Description
Centrifuge briefly prior to opening.
Rims1 is a RAS gene superfamily member that regulates synaptic vesicle exocytosis. Rims1 also plays a role in the regulation of voltage-gated calcium channels during neurotransmitter and insulin release. Mutations in the Rims1 gene have suggested a role cognition and have been identified as the cause of cone-rod dystrophy type 7. Further, Rims1 may act as scaffold protein that regulates neurotransmitter release at the active zone. Rims1 may also be essential for maintaining normal probability of neurotransmitter release and for regulating release during short-term synaptic plasticity. Rims1 also plays a role in dendrite formation by melanocytes. Multiple transcript variants encoding different isoforms have been described for this Rims1. Diseases associated with RIMS1 include Cone-Rod Dystrophy 7 and Retinitis Pigmentosa.
Specifications
| RIM1 | |
| Polyclonal | |
| Unconjugated | |
| Rims1 | |
| C030033M19Rik; CORD7; Kiaa0340; mKIAA0340; Nbla00761; Rab3 effector; Rab3 interacting protein 1; Rab-3-interacting molecule 1; rab3-interacting molecule 1; rab-3-interacting protein 1; rab3-interacting protein 1; Rab-3-interacting protein 2; RAB3-interacting protein 2; Rab3ip1; RAB3IP2; regulating synaptic membrane exocytosis 1; regulating synaptic membrane exocytosis 1 beta; regulating synaptic membrane exocytosis protein 1; Rim; RIM 1; RIM1; RIM1a; RIM1alpha; Rim1b protein; Rims1; Serg1; synaptic exocytosis regulator 1 | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 116837, 84556 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Western Blot | |
| 4.11 mg/mL | |
| PBS with 20% glycerol and 0.025% ProClin 300; pH 7 | |
| Q99NE5, Q9JIR4 | |
| Rims1 | |
| Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of mouse RIM1. The exact sequence is proprietary. | |
| 100 μL | |
| Primary | |
| Mouse, Rat | |
| Antibody | |
| IgG |
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