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Invitrogen™ RIP3 Monoclonal Antibody (C1), Invitrogen™
Mouse Monoclonal Antibody
€ 185.00 - € 448.00
Specifications
| Antigen | RIP3 |
|---|---|
| Clone | C1 |
| Concentration | 1 mg/mL |
| Applications | Western Blot |
| Classification | Monoclonal |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|
17900093
|
Invitrogen™
MA550917 |
200 μL |
€ 448.00
200µL |
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|
17989512
|
Invitrogen™
MA550918 |
20 μL |
€ 185.00
20µL |
Please sign in to purchase this item. Need a web account? Register with us today! | |||||
Description
RIPK3 is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases, which contains a C-terminal domain unique from other RIP family members. RIPK3 is predominantly localized to the cytoplasm, and specifically, are colocalized in the mitochondrion which can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. RIPK3 is a component of the tumor necrosis factor (TNF) receptor-I signaling complex, and can induce apoptosis and weakly activate the NF-kappaB transcription factor and caspase-8 prevents RIPK3-dependent necrosis without inducing apoptosis by functioning in a proteolytically active complex with CFLAR and that this complex is required for the protective function.Specifications
| RIP3 | |
| 1 mg/mL | |
| Monoclonal | |
| Liquid | |
| RUO | |
| PBS with 50% glycerol and 0.05% Proclin 300; pH 7.4 | |
| 2610528K09Rik; AW107945; Hcyp2; Homocysteine respondent protein HCYP2; mRIP3; receptor interacting protein 3; receptor interacting serine/threonine kinase 3; receptor-interacting protein 3; receptor-interacting serine/threonine-protein kinase 3; receptor-interacting serine-threonine kinase 3; Rip3; RIP-3; Ripk3; RIP-like protein kinase 3 | |
| RIPK3 | |
| IgG2b κ | |
| Protein A/G | |
| RIPK3 |
| C1 | |
| Western Blot | |
| Unconjugated | |
| Mouse | |
| Human, Rat | |
| Q9Y572, Q9Z2P5 | |
| 11035, 246240 | |
| Recombinant Rat RIPK3 protein, Val50-Pro272 (Accession #Q9Z2P5). | |
| Primary | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
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