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  4. Invitrogen™ Human RIPK3, GST Tag Recombinant Protein

Invitrogen™ Human RIPK3, GST Tag Recombinant Protein

Product Code. 15479023
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Quantity:
10 μg
Unit Size:
10µg
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Product Code. 15479023

Brand: Invitrogen™ PV6397

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This item is not returnable. View return policy

Description

Recombinant Protein

For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 μg, 10 μg and 20 μg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 μL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase. Recombinant full-length human RIPK3 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. Validated in LanthaScreen™ Kinase Binding Assay Protocols available for simple use and optimized performance Multiple pack sizes available for convenient use Related Product:LanthaScreen™ Eu Kinase Binding Assay Protein Form: Recombinant, Full Length The gene accession number for RIPK3 is NP_006862.2.

RIPK3 is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases, which contains a C-terminal domain unique from other RIP family members. RIPK3 is predominantly localized to the cytoplasm, and specifically, are colocalized in the mitochondrion which can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. RIPK3 is a component of the tumor necrosis factor (TNF) receptor-I signaling complex, and can induce apoptosis and weakly activate the NF-kappaB transcription factor and caspase-8 prevents RIPK3-dependent necrosis without inducing apoptosis by functioning in a proteolytically active complex with CFLAR and that this complex is required for the protective function.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number Q9Y572
Concentration See Label
For Use With (Application) Kinase Assay
Formulation 50mM tris HCl with 0.1mM EDTA, 10mM glutathione, 25% glycerol, 0.25mM DTT, 150mM NaCl, 0.1mM PMSF and no preservative; pH 7.5
Gene ID (Entrez) 11035
Molecular Weight (g/mol) 83.2 kDa
Name Human RIPK3, GST Tag
pH Range 7.5
Purification Method Purified
Quantity 10 μg
Storage Requirements -80°C, Avoid Freeze/Thaw Cycles
Regulatory Status RUO
Gene Alias 2610528K09Rik; AW107945; Hcyp2; Homocysteine respondent protein HCYP2; mRIP3; receptor interacting protein 3; receptor interacting serine/threonine kinase 3; receptor-interacting protein 3; receptor-interacting serine/threonine-protein kinase 3; receptor-interacting serine-threonine kinase 3; Rip3; RIP-3; Ripk3; RIP-like protein kinase 3
Common Name RIP3
Gene Symbol RIPK3
Product Type Protein
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag GST-tag
Sequence Full length
Content And Storage -80°C, Avoid Freeze/Thaw Cycles
Assay Entry Biochemical binding/kinetic
Kinase Group Serine/Threonine Kinase
Target Entry RIPK3
Expression System Baculovirus
Protein Family Kinases & Inhibitors
Protein Form Recombinant, Full Length
Form Liquid
Protein Subtype Serine/Threonine Kinases
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