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Ristocetin Sulfate Salt, MP Biomedicals™

Product Code. 11445422 Shop All MP Biomedicals Products
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25 mg
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25mg
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11445422 25 mg 25mg
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Product Code. 11445422 Supplier MP Biomedicals Supplier No. 0219548925

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Description

Active against gram-positive and gram-negative bacteria. Ristocetin Sulfate Salt, MP Biomedicals is an antibiotic that belongs to the class III glycopeptides. It can be used in chromatography. Ristocetin has platelet aggregating activity and has been used

Ristocetin A is structurally related to the glycopeptide antibiotics Teicoplanin and vancomycin. It activates platelets and has been used in platelet aggregation studies.

  • Ristocetin-induced platelet agglutination (RIPA) is decreased in patients undergoing chronic hemodialysis
  • Together with increased plasma glycocalicin levels (a product of enzymatic cleavage of GPIb), RIPA may contribute to diminished platelet adhesion to vascular subendothelium and increased bleeding associated with uremia
  • Addition of ristocetin and vWf caused specific agglutination of rGPIbα-liposomes supporting the potential use of rGPIbα-liposomes to enhance platelet function in vivo and support hemostasis in thrombocytopenic individuals
  • Studies have demonstrated that Ristocentin A dimerizes and creates two binding sites for cell wall peptides
TRUSTED_SUSTAINABILITY

Specifications

Physical Form Powder
CAS 1404-55-3
Quantity 25 mg
Molecular Formula C95H112N8O48S
Synonym Ristomycin monosulfate
Solubility Information Soluble in 1 N HCl (50mg/mL - clear and colorless to pale yellow); soluble in water (clear 5mg+ 0.25mL, amber solution).
InChI Key HHRPQUHYQBGHHF-ADHWPEJWSA-N
SMILES CC1C(C(CC(O1)OC2C3C(=O)NC(C4=CC(=CC(=C4C5=C(C=CC(=C5)C(C(=O)N3)NC(=O)C6C7=CC(=C(C(=C7)OC8=CC=C2C=C8)OC9C(C(C(C(O9)COC1C(C(C(C(O1)C)O)O)O)O)O)OC1C(C(C(C(O1)CO)O)O)OC1C(C(C(CO1)O)O)O)OC1=CC=C(C=C1)C(C1C(=O)NC(C2=CC(=C(C(=C2)O)C)OC2=C(C=CC(=C2)C(C(=O)N1)N)O)
Molecular Weight (g/mol) 2166.009
PubChem CID 46783382
Formula Weight 2166.0
Percent Purity ≥90% Ristocetin A
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