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Invitrogen™ Rituximab Chimeric Recombinant Rabbit Monoclonal Antibody (10F381 (rituximab))
Rabbit Recombinant Monoclonal Antibody
Brand: Invitrogen™ MA547774
This item is not returnable.
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Description
Specificity: CD20 (Human B-lymphocyte-restricted differentiation antigen, Bp35), is a hydrophobic transmembrane protein with a molecular weight of approximately 35 kDa located on pre-B and mature B lymphocytes, and most B-cell non-Hodgkin's lymphomas, but is not found on stem cells, pro-B cells, normal plasma cells or other normal tissues.
Rituximab (Rituxan) is a humanized monoclonal antibody that is approved by the U.S. Food and Drug Administration for the treatment of patients with certain autoimmune diseases and types of cancer, such as non-Hodgkin's lymphoma, chronic lymphocytic leukemia, rheumatoid arthritis, idiopathic thrombocytopenic purpura, and pemphigus vulgaris. Rituximab is a chimeric monoclonal antibody against the protein CD20, which is primarily found on the surface of immune system B cells. When it binds to this protein it triggers cell death.
Specifications
| Rituximab Chimeric | |
| Recombinant Monoclonal | |
| 1 mg/mL | |
| PBS with 0.02% ProClin 300 | |
| P31358, P32763 | |
| Rabbit | |
| Protein A | |
| RUO | |
| 102144354, 1043, 714429 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Flow Cytometry | |
| 10F381 (rituximab) | |
| Unconjugated | |
| CD52 | |
| IDEC-C2B8; Rituxan | |
| Human lymphoblastoid cell line SB. | |
| 200 μg | |
| Primary | |
| Human, Rhesus Macaque, Cynomolgus Monkey | |
| Antibody | |
| IgG κ |
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