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Tocris Bioscience™ RKI 1447 dihydrochloride
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Potent and selective ROCK inhibitor; antitumor

Brand:  Tocris Bioscience™ 5061/10

Encompass

Product Code. 15716615

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Description

Description

RKI 1447 dihydrochloride is a potent and selective ROCK inhibitor (IC50 values are 6.2 and 14.5 nM for ROCK2 and ROCK1 respectively); suppresses phosphorylation of ROCK substrates MLC-2 and MYPT-1 in human cancer cells, but has no effect on the phosphorylation levels of Akt, MEK, and S6 kinase. Displays anti-invasive and antitumor activities in breast cancer cells.
Specifications

Specifications

>99%
1782109-09-4
10 mg
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