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RNF144B Mouse anti-Human, Clone: OTI11F4, lyophilized, TrueMAB™
Mouse Monoclonal Antibody
Brand: Origene Technologies CF500699
This item is not returnable.
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Description
Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO
E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 and UBE2L6 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates such as LCMT2, thereby promoting their degradation. Induces apoptosis via a p53/TP53-dependent but caspase-independent mechanism. However, its overexpression also produces a decrease of the ubiquitin-dependent stability of BAX, a pro-apoptotic protein, ultimately leading to protection of cell death; But, it is not an anti-apoptotic protein per se.Specifications
| RNF144B | |
| Monoclonal | |
| Unconjugated | |
| RNF144B | |
| IBRDC2, PIR2, bA528A10.3, p53RFP | |
| Mouse | |
| Affinity Chromatography | |
| RUO | |
| 255488 | |
| -20° C, Avoid Freeze/Thaw Cycles | |
| Lyophilized |
| Flow Cytometry, Immunocytochemistry, Immunofluorescence, Western Blot | |
| OTI11F4 | |
| PBS with 8% trehalose and no preservative; pH 7.3 | |
| Q7Z419 | |
| RNF144B | |
| Human recombit protein fragment corresponding to amino acids 1-256 of human RNF144B produced in E.coli | |
| 100 μg | |
| Primary | |
| Human | |
| Antibody | |
| IgG1 |
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