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Rolapitant, MedChemExpress

Product Code. 16492287
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Product Code. 16492287

Brand: Medchem Express HY14751

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Description

MedChemExpress Rolapitant (SCH619734) is a potent, selective, long-acting and orally active neurokinin 1 (NK1) receptor antagonist with a Ki of 0.66 nM. Rolapitant does not interact with CYP3A4. Rolapitant shows potent anti-emetic activity in a ferret emesis model.

Rolapitant (SCH619734) is a potent, selective, long-acting and orally active neurokinin 1 (NK1) receptor antagonist with a Ki of 0.66 nM. Rolapitant does not interact with CYP3A4. Rolapitant shows potent anti-emetic activity in a ferret emesis model.

Specifications

Chemical Name or Material Rolapitant
CAS 552292-08-7
Color Off-White
Purity Grade Notes Research
Molecular Formula C25H26F6N2O2
Quantity 50 mg
Synonym SCH619734
Solubility Information DMSO : ≥ 30 mg/mL (59.94 mM)
SMILES C[C@@](C1=CC(C(F)(F)F)=CC(C(F)(F)F)=C1)([H])OC[C@@]2(C3=CC=CC=C3)CC[C@@](CCC4=O)(N4)CN2
Molecular Weight (g/mol) 500.48
Formula Weight 500.48
Percent Purity 98.65%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-programmed cell death
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Research purposes only

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