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Description
Immunogen sequence: PDTMFCAQQI HIPPELPDIL KQFTKAAIRT QPADVLRWSA GYFSALSRGD PLPVKDRMEM PTATQKTDTG LTQGLL Highest antigen sequence identity to the following orthologs: Mouse - 96%, Rat - 96%.
Principal Names: ROPN1L; Ropporin-1 like; ASP; AKAP-associated sperm protein; Official Gene Symbol: ROPN1L Gene ID: 83853 (human) Gene Map Locus: 5p15.2 (human) AKAPs act as scaffolding proteinscoordinating phosphatase/kinase signaling at the cytoskeleton. They interact with PKAs and anchor them to specific sub-cellular compartments and participate in multiple cellular processes including growth, metabolism and differentiation. ASP, a 26 kDa protein, is a novel AKAP-interacting protein. It interacts with the amphipathic helix of AKAP3 and facilitates AKAP3-PKA interactions. It consists of a conserved N-terminal AKAP-binding domain and a central cysteine-rich Fz domain. It is specifically expressed in the sperms and might play a significant role in sperm motility and also facilitate cytoskeletal reorganization during spermiogenesis.
Specifications
Specifications
| Antigen | ROPN1L |
| Applications | Immunohistochemistry (Paraffin), Western Blot |
| Classification | Polyclonal |
| Concentration | 0.1 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 |
| Gene | Ropn1l |
| Gene Accession No. | Q96C74 |
| Gene Alias | Akapasp; AKAP-associated sperm protein; A-kinase anchoring protein-associated sperm protein; ASP; AV047578; radial spoke head 11 homolog; rhophilin associated tail protein 1 like; rhophilin associated tail protein 1-like; ROPN1L; ROPN1-like protein; ropporin 1-like; ropporin-1-like protein; RSPH11 |
| Gene Symbols | Ropn1l |
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