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RQ-00203078, MedChemExpress

Product Code. 16480038
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Quantity:
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10 mg
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Product Code. 16480038

Brand: Medchem Express HY18662

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Description

MedChemExpress RQ-00203078 is a highly selective, potent and orally active TRPM8 antagonist with IC50s of 5.3 nM and 8.3 nM for rat and human TRPM8 channels, respectively. RQ-00203078 shows little inhibitory action against TRPV1, TRPA1, TRPV4, or TRPM2 channels.

RQ-00203078 is a highly selective, potent and orally active TRPM8 antagonist with IC50s of 5.3 nM and 8.3 nM for rat and human TRPM8 channels, respectively. RQ-00203078 shows little inhibitory action against TRPV1, TRPA1, TRPV4, or TRPM2 channels.

Specifications

Chemical Name or Material RQ-00203078
CAS 1254205-52-1
Color White
Purity Grade Notes Research
Molecular Formula C21H13ClF6N2O5S
Quantity 5 mg
Solubility Information DMSO : ≥ 38 mg/mL (68.49 mM)
SMILES O=C(O)C1=CC=C(S(=O)(N(C2=NC=C(C(F)(F)F)C=C2Cl)CC3=CC=C(OC(F)(F)F)C=C3)=O)C=C1
Molecular Weight (g/mol) 554.85
Formula Weight 554.85
Percent Purity 99.74%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-programmed cell death
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Research purposes only

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