missing translation for 'onlineSavingsMsg'
Learn More
Learn More
RSPO1 Monoclonal Antibody (OTI2B11), TrueMAB™, OriGene
Mouse Monoclonal Antibody
Brand: Origene Technologies TA804459
This item is not returnable.
View return policy
Description
RSPO1 is a member of a family of secreted growth factors that can operate through the canonical Wnt signaling pathway by stabilizing the intracellular beta-catenin, thereby regulating functions mediated by beta-catenin such as cell fate decisions and embryonic patterning. RSPO1 was recently identified through linkage analysis to be involved in sex determination and mammalian ovarian development. RSPO1 is thought to regulate cellular responsiveness to Wnt ligands by modulating the cell-surface expression of the Wnt co-receptor LRP6 by interfering with the DKK/Kremen-mediated internalization of LRP6 through an interaction with Kremen, resulting in increased LRP6 cell-surface levels. At least two isoforms of RSPO1 are known to exist.Specifications
| RSPO1 | |
| Monoclonal | |
| 1 mg/mL | |
| PBS with 1% BSA, 50% glycerol and 0.02% sodium azide | |
| Q2MKA7 | |
| RSPO1 | |
| Human recombit protein fragment corresponding to amino acids 21-263 of human RSPO1 produced in E.coli. | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG2a |
| Western Blot | |
| OTI2B11 | |
| Unconjugated | |
| RSPO1 | |
| CRISTIN3, RSPO | |
| Mouse | |
| Affinity Chromatography | |
| RUO | |
| 284654 | |
| -20° C, Avoid Freeze/Thaw Cycles | |
| Liquid |
Product Content Correction
The Fisher Scientific Encompass Program offers items which are not part of our distribution portfolio. These products typically do not have pictures or detailed descriptions. However, we are committed to improving your shopping experience. Please use the form below to provide feedback related to the content on this product.
Product Title
Spot an opportunity for improvement?Share a Content Correction