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  8. SB 271046 Hydrochloride, MedChemExpress

SB 271046 Hydrochloride, MedChemExpress

Product Code. 16422177
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Quantity:
10 mg
50 mg
Unit Size:
10mg
50mg
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Product Code. 16422177

Brand: Medchem Express HY14336A

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Description

MedChemExpress SB 271046 Hydrochloride (SB 271046A) is a potent, selective and orally active 5-HT6 receptor antagonist with pKi of 9.02, 8.55, and 8.81 for rat, pig and human, respectively. SB 271046 Hydrochloride is over 200 fold selective for the 5-HT6 receptor vs 55 other receptors, binding sites and ion channels. Anticonvulsant activity (EC50=0.16 μM).

SB 271046 Hydrochloride (SB 271046A) is a potent, selective and orally active 5-HT6 receptor antagonist with pKi of 9.02, 8.55, and 8.81 for rat, pig and human, respectively. SB 271046 Hydrochloride is over 200 fold selective for the 5-HT6 receptor vs 55 other receptors, binding sites and ion channels. Anticonvulsant activity (EC50=0.16 μM).

Specifications

Chemical Name or Material SB 271046 Hydrochloride
CAS 209481-24-3
Color White
Purity Grade Notes Research
Molecular Formula C20H23Cl2N3O3S2
Quantity 50 mg
Synonym SB 271046A
Solubility Information DMSO : 50 mg/mL (102.36 mM; Need ultrasonic) ∣H2O : 1 mg/mL (2.05 mM; ultrasonic and warming and heat to 60°C)
SMILES ClC1=CC2=C(C=C1)SC(S(=O)(NC3=CC=C(C(N4CCNCC4)=C3)OC)=O)=C2C.[H]Cl
Molecular Weight (g/mol) 488.45
Formula Weight 488.45
Percent Purity 98.64%
Grade Research
Physical Form Solid
For Use With (Application) Neuroscience-Neuromodulation
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Research purposes only

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