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Invitrogen™ SCLY Polyclonal Antibody
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Product Code. 15925525
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Quantity:
100 μg
Unit Size:
100µg
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15925525 100 μg 100µg
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Product Code. 15925525 Supplier Invitrogen™ Supplier No. PA579958

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Description

Rabbit Polyclonal Antibody

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: U87 Cell, HELA Cell, 293T Cell, MCF-7 Cell, COLO320 Cell, HE1080 Cell.

The SCLY gene encodes selenocysteine lyase, an enzyme involved in selenium metabolism, which plays a critical role in the recycling of selenocysteine from selenoproteins. SCLY catalyzes the conversion of selenocysteine into alanine, releasing selenium for reuse in the biosynthesis of new selenoproteins. It is chiefly active in the liver and kidneys, contributing to maintaining selenium homeostasis, which is vital for numerous biological functions due to selenium's role in antioxidant defense and thyroid hormone metabolism. Alterations in SCLY function or expression can affect selenium levels in the body and are associated with disorders related to oxidative stress and metabolic imbalances. Given the importance of selenium in cellular protection and immune function, SCLY is also of interest in studies focusing on dietary supplementation and disease prevention strategies, particularly in conditions like cancer and cardiovascular diseases where oxidative damage is prevalent.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SCLY
Applications Western Blot
Classification Polyclonal
Concentration 500 μg/mL
Conjugate Unconjugated
Formulation PBS with 5mg BSA and 0.05mg sodium azide, 0.05mg thimerosal
Gene Scly
Gene Accession No. Q96I15
Gene Alias 9830169H08; A930015N15Rik; hSCL; mSCL; SCL; SCLY; Scly1; Scly2; Selenocysteine lyase; selenocysteine lyase; Selenocysteine reductase; selenocysteine reductase
Gene Symbols Scly
Host Species Rabbit
Immunogen A synthetic peptide corresponding to a sequence at the C-terminus of human SCLY (432-445aa QDLKQAVAQLEDQA).
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 51540
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Lyophilized
Isotype IgG
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