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Invitrogen™ SCN1B Polyclonal Antibody
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Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA587614

Product Code. 16576061

  • € 520.00 / 100µL

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Description

Description

Immunogen sequence: GGCVEVDSET EAVYGMTFKI LCISCKRRSE TNAETFTEWT FRQKGTEEFV KILRYENEVL QLEEDERFEG RVVWNGSRGT KDLQDLSIFI TNVTYNHSGD YECHVYRLLF FENYEHNTSV VKKIHIEVVD KGESGAACPF TV; Positive Samples: SH-SY5Y, A-549, HeLa, MCF7, Mouse brain, Rat brain; Cellular Location: Membrane, Single-pass type I membrane protein.

Voltage-gated sodium channels are heteromeric proteins that function in the generation and propagation of action potentials in muscle and neuronal cells. They are composed of one alpha and two beta subunits, where the alpha subunit provides channel activity and the beta-1 subunit modulates the kinetics of channel inactivation. SCN1B encodes a sodium channel beta-1 subunit. Mutations in this gene result in generalized epilepsy with febrile seizures plus, Brugada syndrome 5, and defects in cardiac conduction. Multiple transcript variants encoding different isoforms have been found for this gene.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

SCN1B
Polyclonal
Unconjugated
Scn1b
ATFB13; BRGDA5; GEFSP1; Scn1b; sodium channel beta 1-subunit; sodium channel beta-1 subunit; sodium channel subunit beta-1; sodium channel voltage-gated type 1 beta polypeptide; sodium channel voltage-gated type I beta polypeptide; sodium channel, voltage gated, type I beta subunit; sodium channel, voltage-gated, type 1, beta polypeptide; sodium channel, voltage-gated, type I, beta; sodium channel, voltage-gated, type I, beta polypeptide; sodium channel, voltage-gated, type I, beta subunit; sodium voltage-gated channel beta subunit 1
Rabbit
Affinity Chromatography
RUO
20266, 29686, 6324
-20°C, Avoid Freeze/Thaw Cycles
Liquid
ELISA, Western Blot
0.52 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
P97952, Q00954, Q07699
Scn1b
Recombinant protein (or fragment).
100 μL
Primary
Human, Mouse, Rat
Antibody
IgG
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