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Scopolamine hydrobromide trihydrate, 99%, Thermo Scientific Chemicals

Catalog Number p-191672
35.33 EUR valid until 2024-03-29
Use promo code "21615" to get your promotional price.


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Quantity:
1 g
5 g
25 g
Packaging:
Glass bottle
This item is not returnable. View return policy
To receive the discount customers must purchase three of the same product at list price in a single order to receive 33% discount. There is no limit to the multiples of 3 that customers can buy. Use promo code ”21615” to get your promotional price
6533-68-2
C17H28BrNO7
438.32
MFCD00150066
LACQPOBCQQPVIT-FCFGRTKISA-N
hyoscine hydrobromide trihydrate
131632304
hydrogen (1S,2R,4S,5S)-9-methyl-3-oxa-9-azatricyclo[3.3.1.0²,⁴]nonan-7-yl (2S)-3-hydroxy-2-phenylpropanoate trihydrate bromide
[H+].O.O.O.[Br-].CN1[C@H]2CC(C[C@H]1[C@@H]1O[C@H]21)OC(=O)[C@H](CO)C1=CC=CC=C1
This item is not returnable. View return policy
To receive the discount customers must purchase three of the same product at list price in a single order to receive 33% discount. There is no limit to the multiples of 3 that customers can buy. Use promo code ”21615” to get your promotional price
6533-68-2
C17H28BrNO7
438.32
MFCD00150066
LACQPOBCQQPVIT-FCFGRTKISA-N
hyoscine hydrobromide trihydrate
131632304
hydrogen (1S,2R,4S,5S)-9-methyl-3-oxa-9-azatricyclo[3.3.1.0²,⁴]nonan-7-yl (2S)-3-hydroxy-2-phenylpropanoate trihydrate bromide
[H+].O.O.O.[Br-].CN1[C@H]2CC(C[C@H]1[C@@H]1O[C@H]21)OC(=O)[C@H](CO)C1=CC=CC=C1

Scopolamine hydrobromide trihydrate, CAS # 6533-68-2, is the trihydrate form of scopolamine hydrobromide that shows competitive anti-muscarinic activity by blocking the actions of endogenous acetylcholine or exogenous agonists. It also shows anti-spasmodic and anti-emetic activities.

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Information

• Scopolamine hydrobromide trihydrate is a salt form of scopolamine, a tropane alkaloid derived from plants of the nightshade family (Solanaceae), mainly Hyoscyamus niger and Atropa belladonna
• Scopolamine hydrobromide trihydrate, demonstrates competitive anti-muscarinic activity blocking the actions of endogenous acetylcholine or exogenous agonists
• It also shows anti-spasmodic and anti-emetic activities

Applications

• It has been described that scopolamine inhibits muscarinic acetylcholine receptors (mAChRs) with some selectivity for M1 mAChRs
• It is structurally similar to acetylcholine and can antagonize acetylcholine activity mediated by muscarinic receptors located on structures innervated by postganglionic cholinergic nerves and on smooth muscles (that respond to acetylcholine but lack cholinergic innervation)
• Scopolamine hydrobromide trihydrate can induce amnesia in laboratory animals and so it is frequently used in animal models of memory deficit
• Scopolamine hydrobromide trihydrate is used to induce cognitive deficits in animal models of Alzheimer’s disease
• Scopolamine, has been employed in several studies to understand, identify, and characterize biological targets for Alzheimer's disease

TRUSTED_SUSTAINABILITY
Melting Point 194.0°C to 197.0°C
Color White or Colorless
Infrared Spectrum Authentic
Assay Percent Range 99%
Packaging Glass bottle
Quantity 1 g
Beilstein 27, 102
Merck Index 14, 8406
Specific Rotation Condition −27° (20°C c=5,H2O)
Specific Rotation − 27.00
Solubility Information Solubility in water: 700g/L water (20°C). Other solubilities: 1g/20 mL alcohol,slightly soluble in chloroform,practically insoluble in ether
Formula Weight 438.3
Percent Purity 99%
Physical Form Crystalline Powder or Crystals
Chemical Name or Material Scopolamine hydrobromide trihydrate, 99%
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compliance-icons
Product Identifier
  • Scopolamine hydrobromide trihydrate
Signal Word
  • Danger
Hazard Category
  • Acute toxicity Category 1
  • Acute toxicity Category 2
Hazard Statement
  • H310-Fatal in contact with skin.
  • H330-Fatal if inhaled.
  • H300-Fatal if swallowed.
Precautionary Statement
  • P280-Wear protective gloves/protective clothing/eye protection/face protection.
  • P301+P310-IF SWALLOWED: Immediately call a POISON CENTER/doctor /
  • P302+P352-IF ON SKIN: Wash with plenty of water/.
  • P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
  • P310-Immediately call a POISON CENTER/doctor/.
  • P361-Take off immediately all contaminated clothing.

RUO – Research Use Only

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