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Invitrogen™ SCRN3 Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA589813
This item is not returnable.
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Description
Immunogen sequence: EVCDEEALLG MDLVRLGLER ADTAEKALNV IVDLLEKYGQ GGNCTEGRMV FSYHNSFLIA DRNEAWILET AGKYWAAEKV QEGVRNISNQ LSITTKIARE HPDMRNYAKR KGWWDGKKEF DFAAAYSYLD TAKMMTSSGR YCEGYKLLNK HKGNITFETM MEILRDKPSG INMEGEFLTT ASMVSILPQD SSLPCIHFFT GTPDPERSVF KPFIFVPHIS QLLDTSSPTF ELEDLVKKKS HFKPDRRHPL YQKHQQALEV VNNNEEKAKI MLDNMRKLEK ELFREMESIL QNKHLDVEKI VNLFPQCTKD E; Positive Samples: HepG2, A-549, 293T.
SCRN3 is a member of the secernin family of proteins which includes the homologous SCRN1, a protein that was first identified as being involved in the regulation of exocytosis from peritoneal mast cells. Little is known of SCRN3, but studies have shown that SCRN1 may possess epitopes that function as tumor-associated antigens in gastric cancers and increased SCRN1 expression in patients with colorectal cancer correlated with poor prognosis, suggesting that SCRN3 may also be involved in protein secretion or the regulation of cell growth.
Specifications
| SCRN3 | |
| Polyclonal | |
| Unconjugated | |
| Scrn3 | |
| 4833415E20Rik; AI427019; AV002033; Scrn3; secernin 3; secernin-3; Ses3 | |
| Rabbit | |
| Affinity chromatography | |
| RUO | |
| 311731, 74616, 79634 | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Liquid |
| ELISA, Western Blot, Immunocytochemistry | |
| 3.14 mg/mL | |
| PBS with 50% glycerol and 0.01% thimerosal; pH 7.3 | |
| Q0VDG4, Q3TMH2 | |
| Scrn3 | |
| Recombinant fusion protein containing a sequence corresponding to amino acids 100-410 of human SCRN3 (NP_0788592). | |
| 100 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |
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