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Invitrogen™ SDCCAG8 Polyclonal Antibody

Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA5110911
This item is not returnable.
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Description
Immunogen sequence: AKSPENSTLE EILGQYQRSL REHASRSIHQ LTCALKEGDV TIGEDAPNLS FSTSVGNEDA RTAWPELQQS HAVNQLKDLL RQQADKESEV Highest antigen sequence indentity to the following orthologs: Rat - 68%, Mouse - 70%.
SDCCAG8 (serologically defined colon cancer antigen 8), also known as CCCAP (centrosomal colon cancer autoantigen protein), HSPC085 or NY-CO-8, is a 713 amino acid cytoplasmic protein that is expressed in thymus, prostate, testis, ovary, small intestine, colon, mucosa and renal cancer tumors. Existing as a homodimer, SDCCAG8 localizes to centrioles and interacts with oral-facial-digital syndrome 1 (ODF1), which is associated with nephronophthisis-related ciliopathies (NPHP-RC), a recessive disorder that is characterized by dysplasia or degeneration of the kidney, retina and cerebellum. SDCCAG8 exists as four alternatively spliced isoforms and is encoded by a gene located on humanc chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome.
Specifications
| SDCCAG8 | |
| Polyclonal | |
| Unconjugated | |
| SDCCAG8 | |
| 2700048G21Rik; 5730470G24Rik; Antigen NY-CO-8; BBS16; CCCAP; CCCAP SLSN7; centrosomal colon cancer autoantigen protein; hCCCAP; HSPC085; mCCCAP; NPHP10; NY-CO-8; SDCCAG8; Serologically defined colon cancer antigen 8; serologically defined colon cancer antigen 8 homolog; SHH signaling and ciliogenesis regulator sdccag8; si:dkey-60b15.1; slinky; SLSN7 | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 10806 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Immunocytochemistry | |
| 0.4 mg/mL | |
| PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 | |
| Q86SQ7 | |
| SDCCAG8 | |
| Recombinant Protein corresonding to Human SDCCAG8. Recombinant protein control fragment (Product #RP-105761). | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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