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SDHB Monoclonal Antibody (OTI2A1), TrueMAB™, OriGene
Mouse Monoclonal Antibody
Brand: Origene Technologies TA808103
This item is not returnable.
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Description
Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme. Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma, and support a link between mitochondrial dysfunction and tumorigenesis.Specifications
| SDHB | |
| Monoclonal | |
| 1 mg/mL | |
| PBS with 1% BSA, 50% glycerol and 0.02% sodium azide | |
| P21912 | |
| SDHB | |
| Full length human recombit protein of human SDHB produced in E.coli. | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG1 |
| Immunohistochemistry (Paraffin), Western Blot | |
| OTI2A1 | |
| Unconjugated | |
| SDHB | |
| CWS2, IP, PGL4, SDH, SDH1, SDH2, SDHIP | |
| Mouse | |
| Affinity Chromatography | |
| RUO | |
| 6390 | |
| -20° C, Avoid Freeze/Thaw Cycles | |
| Liquid |
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