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Invitrogen™ SDHB Polyclonal Antibody
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Product Code. 16359004
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Quantity:
100 μL
Unit Size:
100µL
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16359004 100 μL 100µL
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Product Code. 16359004 Supplier Invitrogen™ Supplier No. PA582039

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Description

Rabbit Polyclonal Antibody

Immunogen sequence: EGKQQYLQSI EEREKLDGLY ECILCACCST SCPSYWWNGD KYLGPAVLMQ AYRWMIDSRD DFTEERLAKL QDPFSLYRCH TIMNCTRTCP KGLNPGKAIA EIKKMMATY Highest antigen sequence indentity to the following orthologs: Rat - 97%, Mouse - 97%.

Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme. Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma, and support a link between mitochondrial dysfunction and tumorigenesis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SDHB
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Sdhb
Gene Accession No. P21912, Q9CQA3
Gene Alias 0710008N11Rik; CWS2; fj46d06; FLJ92337; I79_022285; Ip; iron-sulfur subunit; iron-sulfur subunit of complex II; OTTHUMP00000044624; PGL4; SDH; SDH1; SDH2; Sdhb; SDHB protein; SDHB; sdhB; SDHIP; succinate dehydrogenase [ubiquinone] iron-sulfur subunit; Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; succinate dehydrogenase complex iron sulfur subunit B; succinate dehydrogenase complex subunit B; succinate dehydrogenase complex subunit B, iron sulfur (Ip); succinate dehydrogenase complex, subunit B, iron sulfur (Ip); succinate dehydrogenase Ip subunit; succinate dehydrogenase iron-protein subunit; wu:fj46d06
Gene Symbols Sdhb
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human SDHB. Recombinant protein control fragment (Product #RP-102231).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6390, 67680
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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