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Invitrogen™ SDHB Recombinant Rabbit Monoclonal Antibody (9S1A0)
Rabbit Recombinant Monoclonal Antibody
Brand: Invitrogen™ MA535191
This item is not returnable.
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Description
Immunogen sequence: DGLYECILCA CCSTSCPSYW WNGDKYLGPA VLMQAYRWMI DSRDDFTEER LAKLQDPFSL YRCHTIMNCT RTCPKGLNPG KAIAEIKKMM ATYKEKKASV.
Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme. Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma, and support a link between mitochondrial dysfunction and tumorigenesis.
Specifications
| SDHB | |
| Recombinant Monoclonal | |
| 0.35 mg/mL | |
| PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3 | |
| P21912, P21913, Q9CQA3 | |
| Sdhb | |
| A synthetic peptide corresponding to a sequence within amino acids 181-280 of human SDHB (P21912). | |
| 100 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |
| ELISA, Western Blot | |
| 9S1A0 | |
| Unconjugated | |
| Sdhb | |
| 0710008N11Rik; CWS2; fj46d06; FLJ92337; I79_022285; Ip; iron-sulfur subunit; iron-sulfur subunit of complex II; OTTHUMP00000044624; PGL4; SDH; SDH1; SDH2; Sdhb; SDHB protein; SDHB; sdhB; SDHIP; succinate dehydrogenase [ubiquinone] iron-sulfur subunit; Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; succinate dehydrogenase complex iron sulfur subunit B; succinate dehydrogenase complex subunit B; succinate dehydrogenase complex subunit B, iron sulfur (Ip); succinate dehydrogenase complex, subunit B, iron sulfur (Ip); succinate dehydrogenase Ip subunit; succinate dehydrogenase iron-protein subunit; wu:fj46d06 | |
| Rabbit | |
| Affinity chromatography | |
| RUO | |
| 298596, 6390, 67680 | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Liquid |
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