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Invitrogen™ Separase Polyclonal Antibody

Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA5139984
Description
Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user. Immunogen sequence: TQKAAVETSF LDYGENLVQK WQVLSEVLSC SEKLVCHLGR LGSVSEAKAF CLEALKLTTK LQIPRQCALF LVLKGELELA RNDIDLCQSD LQQVLFLLES CTEFGGVTQH LDSVKKVHLQ KGKQQAQVPC PPQLPEEELF LRGPALELVA Highest antigen sequence indentity to the following orthologs: Mouse - 84%, Rat - 85%.
Caspase-like protease, which plays a central role in the chromosome segregation by cleaving the SCC1/RAD21 subunit of the cohesin complex at the onset of anaphase. During most of the cell cycle, it is inactivated by different mechanisms.
Specifications
| Separase | |
| Polyclonal | |
| Unconjugated | |
| ESPL1 | |
| AL024103; AU045071; Caspase-like protein ESPL1; Cerp; Cut1/ESP1 related protein; ESP1; ESPL1; extra spindle pole bodies 1 (S. cerevisiae); extra spindle pole bodies 1, separase; extra spindle pole bodies homolog 1; extra spindle pole bodies homolog 1 (S. cerevisiae); extra spindle pole bodies like 1, separase; extra spindle poles like 1; extra spindle poles-like 1 protein; FLJ46492; KIAA0165; PRCE; SEPA; separase; Separin; separin, cysteine protease; SSE | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 9700 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Immunohistochemistry (Paraffin) | |
| 0.2 mg/mL | |
| PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 | |
| Q14674 | |
| ESPL1 | |
| Recombinant protein corresponding to Human ESPL1. Recombinant protein control fragment (Product #RP-109327). | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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