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  6. Invitrogen™ Septin 2 Recombinant Rabbit Monoclonal Antibody (24GB1525)

Invitrogen™ Septin 2 Recombinant Rabbit Monoclonal Antibody (24GB1525)
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Product Code. 30275486
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30275486 100 μL 100µL
30275606 20 μL 20µL
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Product Code. 30275486 Supplier Invitrogen™ Supplier No. MA557708

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Description

Rabbit Recombinant Monoclonal Antibody

Septin 2 Recombinant Monoclonal Antibody for Western Blot, Flow

Septin 2 is a filament-forming cytoskeletal GTPase. Septin 2 is required for normal organization of the actin cytoskeleton and plays a role in the biogenesis of polarized columnar-shaped epithelium by maintaining polyglutamylated microtubules, thus facilitating efficient vesicle transport, and by impeding MAP4 binding to tubulin. It is required for the progression through mitosis, and it forms a scaffold at the midplane of the mitotic splindle required to maintain CENPE localization at kinetochores and consequently chromosome congression. During anaphase, Septin 2 may be required for chromosome segregation and spindle elongation. Septin 2 also plays a role in ciliogenesis and collective cell movements.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Septin 2
Applications Flow Cytometry, Western Blot, Immunocytochemistry
Classification Recombinant Monoclonal
Clone 24GB1525
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene SEPTIN2
Gene Accession No. P42208, Q15019, Q91Y81
Gene Alias 2-Sep; AW208991; DIFF6; hNedd5; KIAA0158; mKIAA0158; NEDD5; Nedd-5; Neural precursor cell expressed developmentally down-regulated protein 5; neural precursor cell expressed, developmentally down-regulated 5; neural precursor cell expressed, developmentally down-regulated gene 5; Pnutl3; Sept2; septin 2; Septin2; septin-2; Vascular endothelial cell specific protein 11; Vesp11
Gene Symbols SEPTIN2
Host Species Rabbit
Immunogen A synthesized peptide derived from human Septin 2 (aa 250-300).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 117515, 18000, 4735
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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