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SESN1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Product Code. 16881275 Shop All Proteintech Products
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150 μL
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20µL
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16881275 150 μL 150µL
16891275 20 μL 20µL
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Product Code. 16881275 Supplier Proteintech Supplier No. 216681AP150UL

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Description

Rabbit Polyclonal Antibody

This gene encodes a member of the sestrin family. Sestrins are induced by the p53 tumor suppressor protein and play a role in the cellular response to DNA damage and oxidative stress. The encoded protein mediates p53 inhibition of cell growth by activating AMP-activated protein kinase, which results in the inhibition of the mammalian target of rapamycin protein. The encoded protein also plays a critical role in antioxidant defense by regenerating overoxidized peroxiredoxins, and the expression of this gene is a potential marker for exposure to radiation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Specifications

Antigen SESN1
Applications Western Blot
Classification Polyclonal
Concentration 0.33 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene SESN1
Gene Accession No. P58006, Q9Y6P5
Gene Alias p53 regulated protein PA26, PA26, RP11 787I22.1, SESN1, SEST1, sestrin 1
Gene Symbols SESN1
Host Species Rabbit
Immunogen SESN1 Fusion Protein Ag16462
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 140742, 27244, 294518
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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