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Invitrogen™ SESN3 Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA592350
This item is not returnable.
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Description
Immunogen sequence: MNRGGGSPSA AANYLLCTNC RKVLRKDKRI RVSQPLTRGP SAFIPEKEVV QANTVDERTN FLVEEYSTSG RLDNITQVMS LHTQYLESFL RSQFYMLRMD GPLPLPYRHY IAIMAAARHQ CSYLINMHVD EFLKTGGIAE WLNGLEYVPQ RLKNLNEINK LLAHRPWLIT KEHIQKLVKT GENNWSLPEL VHAVVLLAHY HALASFVFGS GINPERDPEI SNGFRLISVN NFCVCDLAND NNIENASLSG SNFGIVDSLS ELEALMERMK RLQEEREDEE ASQEEMSTRF EKEKKESLFV VSGDTFHSFP; Positive Samples: HeLa, A-549.
May function as an intracellular leucine sensor that negatively regulates the TORC1 signaling pathway (PubMed:25263562). May also regulate the insulin-receptor signaling pathway through activation of TORC2. This metabolic regulator may also play a role in protection against oxidative and genotoxic stresses.
Specifications
| SESN3 | |
| Polyclonal | |
| Unconjugated | |
| SESN3 | |
| 5630400E15Rik; BC003348; Sesn3; SEST3; sestrin 3; sestrin-3 | |
| Rabbit | |
| Affinity Chromatography | |
| RUO | |
| 143686 | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Liquid |
| ELISA, Western Blot | |
| 1.4 mg/mL | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
| P58005 | |
| SESN3 | |
| Recombinant fusion protein containing a sequence corresponding to amino acids 1-310 of human SESN3 (NP_6532662). | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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